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HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS
专利权人:
ASTRAZENECA AB
发明人:
MCGUIRE HELEN,BIST SHANTA,BIFULCO NEIL,ZHAO LIANG,WU, VE,HUYNH, HOAN,XIONG, HUI,COMITA-PREVOIR, JANELLE,DUSSAUL T, DAEMIAN,CHEN, BRENDAN,DURAND-REVILLE, THOMAS,GULER, SATENIG,GENG, BOLIN
申请号:
TN2014000417
公开号:
TN2014000417A1
申请日:
2014.10.02
申请国别(地区):
TN
年份:
2016
代理人:
摘要:
The present invention is directed to compounds which are beta-lactamase inhibitors. The compounds and their pharmaceutically acceptable salts, are useful in combination with beta-lactam antibiotics, or alone, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to formula (Ia): or a pharmaceutically acceptable salt thereof, wherein the values of R1, R 2, R 3 and R 4 are described herein.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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