[Problem] To provide a medicine inspection device that makes it possible to more smoothly perform similarity determination for determining the presence of a medicine that is similar to a medicine that is individually packed in a wrapper； and a system for individually packaging medicine that includes the medicine inspection device. [Solution] A system (S) for individually packaging medicine is provided with a medicine inspection device (10) that is capable of performing inspection of medicine that is individually packaged using a device (100) for individually packaging medicine or the like. The control device (60) of the medicine inspection device (10) is provided with an inspection database (62) in which images of medicine are stored as master images and is capable of carrying out an inspection task using image matching processing that involves an image acquired by imaging. The control device (60) is also capable of performing similarity determination for determining whether a medicine that is similar to a medicine that is packaged in an individual wrapper is present in the inspection database (62) in a state in which the reference scope of the inspection database is restricted.
