Nakashima, Hiroshi; Inc.;The Brigham and Women's Hospital, Inc.;The Brigham and Womens Hospital
发明人:
NAKASHIMA, Hiroshi,CHIOCCA, Ennio Antonio
申请号：
EP16789977
公开号：
EP3291841A4
申请日:
2016.05.04
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Malignant tumors that are resistant to conventional therapies represent significant therapeutic challenges. An embodiment of the present invention provides a second generation oncolytic virus rQNestin34.5v2 with less toxicity that is more effective at selective killing target cells, such as tumor cells. In various embodiments presented herein, the oncolytic virus described herein is suitable for treatment of glioblastoma, as well as other cancers.
