Idenix Pharmaceuticals LLC;Centre National de la Recherche Scientifique (C.N.R.S.);Université de Montpellier
发明人:
申请号：
EP13776706.7
公开号：
EP2906579B1
申请日:
2013.10.07
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2&prime；-chloro nucleosides according to Formula 2001: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein B, Z and PD are as described herein.
