Jeremy Minshull,Mark Welch,Sridhar Govindrajan,Kate Caves
申请号:
US14683126
公开号:
US09534234B2
申请日:
2015.04.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides polynucleotide vectors for high expression of heterologous genes, and methods for constructing such vectors. Some vectors further comprise novel transposons and transposases that further improve expression. Further disclosed are vectors that can be used in a gene transfer system for stably introducing nucleic acids into the DNA of a cell. The gene transfer systems can be used in methods, for example, but not limited to, gene expression, gene therapy, insertional mutagenesis, or gene discovery.