SETHI DALIP,BAKER BRUCE,PONEMONE VENKATESH,HARRIS KENNETH LEE,LACHER MARKUD D,HEISERMAN JAMES
申请号：
IN201717039350
公开号：
IN201717039350A
申请日:
2017.11.04
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
Disclosed herein are methods of ameliorating or inhibiting critical limb ischemia or a condition associated with critical limb ischemia in a subject whereby such methods comprise identifying a subject having a peripheral vascular disease peripheral arterial disease critical limb ischemia or a condition associated with critical limb ischemia and providing to said subject a composition comprising: a cell population wherein the cell population comprises bone marrow total nucleated cells and red blood cells an anticoagulant and autologous plasma wherein the composition has a viscosity of 1.5 to 5.0 centipoise (cP) measured at 37°C wherein the composition comprises a viable cell dose and wherein said composition is administered to said subject intramuscularly through a standard terminally ported cannula needle or a cannula side ported needle or catheter comprising a plurality of ports and a closed end.
