Christian Welz,Gottfried Stubauer,Andreas Schmarda,Herwig Jennewein,Ingolf Macher,Johannes Ludescher
申请号:
US12374489
公开号:
US08232245B2
申请日:
2007.07.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to pharmaceutical compositions comprising a pharmaceutically acceptable salt of caspofungin as active ingredient being useful for the prevention and/or treatment of fungal infections. The compositions additionally comprise specific bulking agents and small amounts or no amounts of an additional pH modifier and may be in a liquid or solid form, e.g. may be lyophilized compositions. The compositions show good stability and reduced amounts of sub-visible particulate matter formed in solutions which are reconstituted from the lyophilized product.