THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE COMPRISING 2-AMINO-1,3-PROPANAEDIOL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE
A novel therapeutic and prophylactic agent for inflammatory bowel diseases and a method for treating inflammatory bowel diseases. The agent comprises a 2-amino-1,3-propanediol derivative ( e.g ., 2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl-1,3-propanediol hydrochloride) represented by the chemical formula (1) or a pharmaceutically acceptable salt or hydrate thereof: The agent is useful in the treatment or prevention of Crohn's disease, Crohn's disease in large intestine, intestinal Behcet's disease, ulcerative colitis, bleeding rectal ulcer and pouchitis.Novo terapijsko i profilaktičko sredstvo za upalne bolesti crijeva i postupak za liječenje upalnih bolesti crijeva. Sredstvo sadrži derivat 2-amino-1,3-propandiola (npr. 2-amino-2-[4-(3-benziloksifeniltio)-2-klorofenil]etil-1,3-propandiol hidroklorid) predstavljen kemijskom formulom (1) ili njegovu farmaceutski prihvatljivu sol ili hidrat:(Kemijska formula 1)Sredstvo je korisno u liječenju ili prevenciji Chronove bolesti, Chronove bolesti debelog crijeva, intestinalne Behcetove bolesti, ulceroznog kolitisa, rektalnog čira koji krvari i pouchitisa.