The present invention relates to a method for manufacturing an adjuvant composition and a vaccine composition comprising the step of drying based on a spray drying technique. The method comprises the step of forming a powder by mixing and drying a biopolymer and two or more immune supplements. According to the present invention, the composition can be stably dispersed in an aqueous solution and can be stored in a powder form for a long period of time.COPYRIGHT KIPO 2016스프레이 드라잉을 이용하여 건조하는 것을 포함하는, 아주번트 조성물 및 백신 조성물의 제조 방법에 관한 것이다.