The United States of America, as represented by the Secretary, Department of Health &； Human Services;Sirnax, Inc.
发明人:
Bira Arya,Michael R. Simon
申请号：
US16594864
公开号：
US20200022999A1
申请日:
2019.10.07
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A fusion molecule is provided that includes one or more inhibitory nucleic acids, a targeting polypeptide, and a nucleic acid binding moiety. The targeting polypeptide and the nucleic acid binding moiety include specific the amino acid sequences. A fusion molecule is also provided that includes one or more inhibitory nucleic acids, a targeting polypeptide, and a nucleic acid binding moiety adapted to bind a double-stranded RNA or to a small hairpin RNA. The targeting polypeptide being IL6 or IL21 or a fragment thereof.
