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Stable pharmaceutical solution formulations for pressurised metered dose inhalers
专利权人:
Chiesi Farmaceutici S.p.A.
发明人:
Lewis David,Ganderton David,Meakin Brian,Brambilla Gaetano,Ferraris Alessandra
申请号:
HU0302007
公开号:
HU230804B1
申请日:
2000.05.22
申请国别(地区):
HU
年份:
2018
代理人:
摘要:
An aerosol solution composition for use in an aerosol inhaler comprises an active material, a propellant containing a hydrofluoroalkane, a cosolvent and optionally a low volatility component to increase the mass median aerodynamic diameter (MMAD) of the aerosol particles on actuation of the inhaler. The composition is stabilized by using a small amount of mineral acid and a suitable can having part or all of its internal metallic surfaces made of stainless steel, anodized aluminium or lined with an inert organic coating.
来源网站:
中国工程科技知识中心
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