Andreas Hafner,Fritz Blatter,Martin Szelagiewicz,Bernd Siebenhaar
申请号：
US13574005
公开号：
US09249108B2
申请日:
2011.11.21
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A novel solid form of Rosuvastatin comprises as the active ingredient a salt of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)-amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid] and sorbitol. The crystal comprising the two components, and minor amounts of water, shows improved properties such as crystallization behavior and stability.
