Is displayed with the below-mentioned general formula (1) the chemical compound which and/or it features that N- methyl -2- pyrolidone is contained that salt and, 2), the medicine composition of external use.(However, in X formula the hydrogen atom or the chlorine atom is displayed.)下記一般式(1)で表される化合物及び/またはその塩と、2)N-メチル-2-ピロリドンとを含有することを特徴とする、外用の医薬組成物。(但し、式中Xは水素原子または塩素原子を表す。)