[(1H-INDOL-5-YL)-HETEROARYLOXY]-(1-AZA-BICYCLO[3.3.1]NONANES AS CHOLINERGIC LIGANDS OF THE N-ACHR FOR THE TREATMENT OF PSYCHOTIC AND NEURODEGENERATIVE DISORDERS
The present invention relates to 1-aza-bicycloalkyl derivatives of formula (I), to methods for their preparation, to pharmaceutical compositions comprising them, and to their use in the manufacture of a medicament for the treatment and / or delaying the progression of psychotic and neurodegenerative disorders. will be.<；Formula I>；Wherein the substituents are as defined in the specification.N-ACHR, 1-aza-bicyclononane derivative, [(1H-indol-5-yl) -heteroaryloxy]-(1-aza-bicyclo [3.3.1] nonane, psychotic disorder, neurodegenerative disorder본 발명은 하기 화학식 I의 1-아자-비시클로알킬 유도체, 이의 제조 방법, 이를 포함하는 제약 조성물, 및 정신병성 및 신경퇴행성 장애의 치료 및/또는 진행 지연용 의약의 제조에서의 이의 용도에 관한 것이다.<；화학식 I>；상기 식에서, 치환기는 명세서에 정의한 바와 같다.
