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Pharmaceutical Compositions and Therapeutic Methods Employing a Combination of a Manganese Complex Compound and a Non-Manganese Complex Form of the Compound
专利权人:
Rolf Andersson;Jan-Olof Karlsson
发明人:
Jan-Olof Karlsson,Rolf Andersson
申请号:
US13379468
公开号:
US20120101066A1
申请日:
2010.07.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A pharmaceutical composition for treatment of a pathological condition in a patient comprises, as a first component, a manganese complex of Formula I( ), and, as a second component, a non-manganese complex compound of Formula (I), optionally together with one or more physiologically acceptable carriers and/or excipients, wherein X, R, R, R, and R are as defined herein. Methods for treatment of a pathological condition in a patient, for example, a pathological condition caused by the presence of oxygen-derived free radicals, comprises administering to said patient the first component and the second component.
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