AN OBJECT OF THE PRESENT INVENTION IS TO PROVIDE A PHARMACEUTICAL COMPOSITION CONTAINING REBAMIPIDE, WHICH IS UNNECESSARY TO BE RE-DISPERSED, HAS AN ENOUGH TRANSPARENCY, AND EXHIBITS NEUTRAL TO WEAKLY ACIDIC PH NOT TO INJURE THE KERATOCONJUNCTIVA OF A PATIENT SUFFERING FROM DRY EYE. THE PRESENT PHARMACEUTICAL COMPOSITION COMPRISES (1) REBAMIPIDE, (2) AN AMINO SUGAR, AND (3) AN BUFFER AGENT, WHICH HAS NO INORGANIC CATION.