The invention relates to aminopyrazole derivatives of formula (I),wherein A, E, R1and R2are as defined in the description, their preparation and their use as pharmaceutically active compounds.本發明係關於式(I)胺基吡唑衍生物,其中A,E,R1及R2均如說明文中所定義,其製備,及其作為醫藥活性化合物之用途。