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Salt and its crystal of condensation heterocyclic congeners
专利权人:
Kissei Pharmaceutical Co.; Ltd.
发明人:
Hideki Takeuchi,Kazumichi Jo
申请号:
BR112012020110
公开号:
BR112012020110A2
申请日:
2011.02.09
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
fused heterocyclic derivative salt and crystal thereof. The object of the present invention is to improve the solubility of 3- [2-fluoro-5- (2,3-difluoro-6-methoxybenzyloxy) -4-methoxyphenyl] -2,4-dioxo-1,2,3,4 acid tetrahydro-thieno [3,4-d] pyrimidine-5-carboxylic acid. The present invention describes a 3- [2-fluoro-5- (2,3-difluoro-6-methoxybenzyloxy) -4-methoxyphenyl] -2,4-dioxo-1,2,3,4-acid choline salt. tetrahydrothieno [3,4-d] pyrimidine-5-carboxylic, which exhibits optimum solubility and storage stability.sal de derivado heterocíclico fusionado e cristal do mesmo. o objetivo da presente invenção é melhorar a solubilidade do ácido 3-[2-fluoro-5-(2,3-difluoro-6-metoxibenziloxi)-4-metoxifenil]-2,4-dioxo-1,2,3,4-tetraidro-tieno[3,4-d] pirimidina-5-carboxílico. a presente invenção descreve um sal de colina do ácido 3-[2-fluoro-5-(2,3-difluoro-6-metoxibenziloxi)-4-metoxifenil]-2,4-dioxo-1,2,3,4-tetraidrotieno[3,4-d]pirimidina-5-carboxílico, que apresenta uma ótima solubilidade e estabilidade ao armazenamento.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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