The Trustees of The University of Pennsylvania;The Children's Hospital of Philadelphia
发明人:
申请号:
EP15758926.8
公开号:
EP3113777A4
申请日:
2015.03.03
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to methods for treating or preventing a mitral valve disease in a subject in need thereof, comprising administering to the subject an effective amount of a therapeutic agent. The therapeutic agent is capable of suppressing serotonin receptor signaling. The methods may be combined with a mitral valve surgery, serotonin transporter polymorphism genotyping, MV disease diagnosis, and/or an adjunct assay. Also provided are related medicaments, pharmaceutical compositions, and methods for preparing the medicaments.