The present disclosure provides a method and a non-transitory computer readable storage medium for determining a set of personalized metabolic disease healthy foods which includes the following steps. In a nucleic acid detection step, a nucleic acid of a biological sample is detected, and according to a detection result of the nucleic acid, the morbidity of a metabolic disease is accessed. In a blood detection step, a target and at least one healthy index of a blood sample are detected and examined, and according to a detection result of the target whether the metabolic disease has occurred is determined. In a personalized-metabolic-disease-healthy-food-set deciding step, a set of personalized metabolic disease healthy foods is determined according to the morbidity of the metabolic disease accessed in the nucleic acid detection step and at least one healthy index of the blood sample determined in the blood detection step. The set of personalized metabolic disease healthy foods includes a plurality of healthy foods. At least one of the healthy foods is an immunomodulatory protein or a complex of the immunomodulatory protein. This method is provided to a person who has a risk of suffering the metabolic disease.本發明揭露一種個人化新陳代謝疾病保健食品組合的決定方法及非暫態電腦可讀取儲存媒體，以供可能罹患新陳代謝疾病的個人利用。個人化新陳代謝疾病保健食品組合的決定方法包括下列步驟。核酸檢測步驟係檢測生物樣品中的核酸，依據核酸的檢測結果判斷罹患新陳代謝疾病的可能性。血液檢測步驟係檢測血液樣品中的標靶及至少一健康指數，並依據標靶的檢測結果判斷未罹患新陳代謝疾病。個人化新陳代謝疾病保健食品組合決定步驟係依據核酸檢測步驟中的罹患新陳代謝疾病的可能性及血液檢測步驟中的至少一健康指數來決定出一個人化新陳代謝疾病保健食品組合，個人化新陳代謝疾病保健食品組合包括複數個保健食品，至少一保健食品是免疫調節蛋白或免疫調節蛋白的複合物。
