A device and methods mix polymethylmethacrylate bone cement and/or store the starting components of the bone cement. The device comprising: a cartridge with an internal space for mixing the bone cement that is closed on one side by means of a mobile dispensing plunger； a monomer container for a monomer liquid and/or a connector for attachment of a monomer container for a monomer liquid such that the monomer container can be opened appropriately in the device such that the monomer liquid flows from the monomer container into the device； a connecting conduit through which the monomer liquid can be guided into the internal space of the cartridge. A first hollow cylinder is connected to the connecting conduit and a second hollow cylinder is connected, via a vacuum conduit, to the internal space of the cartridge, whereby a pumping plunger is shiftable axially in the first hollow cylinder and is arranged in the first hollow cylinder and a vacuum plunger that is shiftable axially in the second hollow cylinder is arranged in the second hollow cylinder, whereby the pumping plunger and the vacuum plunger may be moved simultaneously.
