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פוליפפטידים ופולינוקליאוטידים והשימוש בהם כיעד לתרופות לייצור תרופות ותכשירים ביולוגים
专利权人:
AMIR TOPORIK;SHIRA WALACH;AMIT NOVIK;MERAV B;ANAT COHEN-DAYAG;CYNTHIA KOIFMAN;LIAT DASSA;GALIT ROTMAN;SHIRLEY SAMEAH-GREENWALD;COMPUGEN LTD.;AVI YESHAH ROSENBERG;ZURIT LEVINE;YARON KINAR;SERGEY NEMZER
发明人:
SHIRA WALACH,ZURIT LEVINE,GALIT ROTMAN,AMIT NOVIK,SHIRLEY SAMEAH-GREENWALD,ANAT COHEN-DAYAG,AMIR TOPORIK,LIAT DASSA,AVI YESHAH ROSENBERG,YARON KINAR,SERGEY NEMZER,CYNTHIA KOIFMAN,MERAV BEIMAN,EVE MONT
申请号:
IL22579413
公开号:
IL225794A
申请日:
2013.04.17
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against C1ORF32 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation is also provided. This invention further relates to the discovery of extracellular domains of C1ORF32 and its variants awhich are suitable targets for cancer therapy, and drug development.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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