Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side-effects

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专利权人:

The Trustees of the University of Pennsylvania

发明人:

Rader, Daniel J.

申请号：

AU2011226862

公开号：

AU2011226862B2

申请日:

2011.09.23

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

#$%^&*AU2011226862B220141002.pdf#####ABSTRACT The present invention provides methods and compositions for treating hyperlipidemia and/or hypercholesterolemia comprising administering to the subject an effective amount of an MTP inhibitor to inhibit hyperlipidemia and/or hypercholesterolemia in said subject, wherein said administration comprises an escalating series of doses of the MPT inhibitor. In some embodiments the method comprises administering at least three stepwise, increasing dosages of the MPT inhibitor to the subject. In some embodiments, the method further comprises the administration of one or more other lipid modifying compounds.

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