A sensor arrangement (100) for detecting information indicative of a physiological substance in a body material (102) of a physiological subject (106), wherein the sensor arrangement (100) comprises a substrate (104), a first sensor structure (202) connected to the substrate (104) and being configured for sensing the physiological substance electrochemically, and a second sensor structure (204) connected to the substrate (104) and being configured for sensing the physiological substance by a luminescence detection.