Khuraseva Anna Borisovna,Хурасева Анна Борисовна,Svyatchenko Kseniya Sergeevna,Святченко Ксения Сергеевна,Polonikov Aleksej Valerevich,Полоников Алексей Валерьевич,Medvedeva Irina Nikolaevna,Медведева
申请号：
RU2016122383
公开号：
RU0002629720C1
申请日:
2016.06.06
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention can be used to predict the risk of polycystic ovarian syndrome (PCOS) formation in adolescent girls. As anamnestic data assess the presence of: hereditary burden on PCOS by both mother and father, burdened family history of type 2 diabetes, burdened heredity for obesity are estimated. The presence of each attribute is scored as 2 points. Also the presence of low ≤2800 g or high ≥4000 g body weight of the child at birth at mature gestation term, maternal gestational diabetes during pregnancy, excess of the mothers body weight during pregnancy, chronic tonsilogenous infections and frequent sore throats, traumatic brain injury, history of neuroinfection, sedentary lifestyle, severe psychoemotional stress in the girl are determined. If present, the attributes are scored as 1 point each. Among the clinical data the presence of: menstrual irregularities in the type of oligo-/amenorrhea for more than 1.5-2 years after menarche, anovulatory cycle, obesity - body mass index (BMI) more than 30 kg/m2, hirsutism is estimated. The presence of each attribute is scored as 3 points. If there is an excess of body weight with a BMI of 26-30 kg/m2, abdominal redistribution of fat deposits, borderline hairiness - 8-14 points on the Ferriman-Gallwey scale, increased greasiness of hair and skin, acne, seborrhea, negroid acanthosis, fibrocystic mastopathy, 2 points are assigned to each feature. 1 point is assigned to the presence of normal body weight, dysfunctional uterine bleeding in the puberty period. Laboratory indicators are identified: in the presence of an increase in the ratio of luteinizing hormone to follicle stimulating hormone (LH/FSH) of more than 2.5, 3 points are assigned. Also, the presence of an elevated level of luteinizing hormone, an increased level of total testosterone, an elevated level of androstenedione, an increase in insulin with an empty stomach, an increased level of glycosylated hemoglobin are also determined. If present,
