Novel this application involves available what medical and health industry can excited particles. More particularly it relates to when penetrating the particle that can generate electronics and/or high-energy photon when Line, γ-penetrate Line, radioactive isotope and/or electron-beam excitation, and its purposes in health care, particularly human medical's health with ionising radiation such as X-. Particle of the invention is made of oxygen-containing inorganic material, particularly oxide, and the material has sufficient density, and can be activated in vitro, in vitro or in vivo by controllable external excitation, to upset, change or destroy target cell, tissue or organ. The invention further relates to the production methods of the particle, and the drug comprising them or medical apparatus composition.本申請涉及可用於醫療衛生行業的新型可激發粒子。更具體來說,它涉及當用電離輻射例如X-射綫、γ-射綫、放射性同位素和/或電子束激發時能夠産生電子和/或高能光子的粒子,及其在醫療衛生、特別是人類醫療衛生中的用途。本發明的粒子由含氧無機材料、特別是氧化物製成,所述材料具有足夠密度,並可以在體外、離體或體內通過可控的外部激發進行激活,以便擾亂、改變或破壞靶細胞、組織或器官。本發明還涉及所述粒子的生産方法,以及包含它們的藥物或醫學裝置組合物。