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Preparation of thioarabinofuranosyl compounds and use thereof
专利权人:
John A. Secrist; III
发明人:
John A. Secrist, III,Kamal N. Tiwari,John A. Montgomery
申请号:
US12710537
公开号:
US08178510B2
申请日:
2010.02.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Patients suffering from cancer are treated by being administered a compound represented by the following formula:wherein each R individually is H or an aliphatic or aromatic acyl group A is selected from the group consisting ofwherein X is selected from the group consisting of hydrogen, fluorine, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano and nitro. The above compounds also inhibit DNA replication in mammalian cells.
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