The invention relates to an electric mousetrap with intelligent detection and safety protection functions, which includes a cavity structure defined by an upper shell and a base and provided with a hole, wherein a power supply module, an intelligent control circuit board, an indication module and a high-voltage generator module are mounted on the upper shell three mutually-independent electrode plates are arranged on the base and all electrically connected with the intelligent control circuit board, and the intelligent control circuit board receives signals transmitted from the electrode plates and controls the indication module and the high-voltage generator module to act correspondingly after processing the signals. The electric mousetrap can intelligently detect the activity condition of a mouse in the mousetrap and electrically shock the mouse, is safe in use and has a good power saving effect.