Sobhana Babu Boga;James J-S Wang;Jagdish A. Desai;Alan B. Cooper;Sie-Mun Lo;Liang Zhu;Joseph M. Kelly;Hugh Y. Zhu;Xin Yao;Yongqi Deng;Abdul-Basit Alhassan;Subrahmanyam Gudipati;Gerald W. S;Xiaolei Gao
发明人:
Sobhana Babu Boga,Joseph M. Kelly,Hugh Y. Zhu,Abdul-Basit Alhassan,Xin Yao,Xiaolei Gao,James J-S Wang,Jagdish A. Desai,Subrahmanyam Gudipati,Sie-Mun Lo,Liang Zhu,Alan B. Cooper,Yongqi Deng,Gerald W. S
申请号：
US13881050
公开号：
US20130237518A1
申请日:
2011.10.24
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed are the ERK inhibitors of formula (1): and the pharmaceutically acceptable salts thereof, wherein: A is a five membered monocyclic heteroaryl ring； and B is a monocyclic heterocycloalkyl ring, or a monocyclic heterocycloalkenyl ring, or a bridged monocyclic heterocycloalkyl ring, or a fused (monocyclic heterocycloalkyl ring) cyclopropyl ring. Also disclosed are methods of treating cancer using the compounds of formula (1).
