Mark M. Menning;Terrence C. Dahl;Munir A. Hussain;Reza Oliyai;Taiyin Yang;Robert A. Lipper;Robert L. Jerzewski
发明人:
Terrence C. Dahl,Munir A. Hussain,Robert A. Lipper,Robert L. Jerzewski,Mark M. Menning,Reza Oliyai,Taiyin Yang
申请号:
US11453122
公开号:
US08598185B2
申请日:
2006.06.13
申请国别(地区):
US
年份:
2013
代理人:
摘要:
In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenofovir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein components 1 and 2 are in a stabilizing configuration. In preferred embodiments component 1 is made by dry granulation.