2-chloro-6,7-dimethoxy-N-5 [5-(1)H- indazolyl]quinazoline-4-amine, N-(1-benzyl-4-piperidinyl)-1H-indazole-5-amine dihydrochloride, 4-[2-(2,3,4,5,6-pentafluorophenyl)acryloyl]cinnamic acid and fasudil hydrochloride for use in repairing corneal perception.
It is intended to provide a novel drug repairing the corneal perception after a corneal surgery and improving the symptoms of dry eye. This drug, which contains an Rho protein inhibitor, is useful for treating depression in corneal perception after a cataract surgery, after an LASIK surgery, after a PRK surgery, or after corneal transplantation, or in association with neuroparalytic keratopathy, corneal ulcer, diabetic keratopathy, etc. and improving dry eye symptoms.