Woolven, Benjamin P.,Lee, Jennifer A.,Jennings, Philip Anthony,Tomlinson, Ian M.,Doyle, Anthony Gerard
申请号:
AU2007211829
公开号:
AU2007211829C9
申请日:
2007.02.01
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention provides a domain antibody construct which binds to human TNF-α, the construct comprising: (a) a domain antibody (dAb) which binds to human TNF-α; (b) a modified hinge region sequence; (c) a human or primate heavy chain constant region sequence having a truncated C