SENDEN TIMOTHY JOHN,KING DAVID WALLACE,STEPHENS ROSS WENTWORTH
申请号：
NZ60908309
公开号：
NZ609083A
申请日:
2009.04.23
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a method for preparing a radiolabeled synthetic polymer, the method comprising contacting a synthetic polymer with a carbon encapsulated nanoparticle composite having a radioactive particulate core in an aqueous medium comprising an electrolyte concentration or pH selected to promote short-range attractive forces between the nanoparticles and the synthetic polymer by attenuating long- range electrostatic repulsive forces, wherein the synthetic polymer is selected from the group consisting of polystyrene, polypropylene, polyurethane, polyvinyl chloride, polyamides, polystyrene sulphonate, teflon, polyester, polyethylene terephthalate, poly(butylene terephthalate) (PBT), poly(ethylene oxide) (PEO), polylactide (PLA), polyglycolide (PGA), poly(lactide-co-glycolide) (PLGA), poly(e-caprolactone), polydioxanone, trimethylene carbonate, polyanhydride, poly[bis(p-carboxyphenoxyl) propane:sebacic acid and wherein the carbon encapsulated nanoparticle composite is a carbon encapsulated 99mTc, 113mIn, 111In, 198Au, 64Cu, 213Bi, 57Co, 51Cr, 165Dy, 169Er, 59Fe, 153Gd, 166Ho, 177Lu, 103Pd, 81Rb, 82Rb, 186Re, 188Re, 75Se, 153Sm, 117mSn, 89Sr, 201Th, 90Y, or 169Y nanoparticle having a diameter of 10 to 500 nanometres.
