細胞壞死抑制劑及其製備方法和用途

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专利权人:

SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY; CHINESE ACADEMY OF SCIENCES

发明人:

MA, DAWEI,马大为,馬大為,JI, YUHUA,季玉华,季玉華,HE, WEIMING,何卫明,何衛明,FANG, CHAO,方超,ZHAO, JINLONG,赵金龙,趙金龍,WANG, KAILIANG,王开亮,王開亮,XIA, SHANGHUA,夏尚华,夏尚華,LI, ZHENG,李征,LI, YING,李盈

申请号：

TW108122214

公开号：

TW202019913A

申请日:

2019.06.25

申请国别(地区):

TW

年份:

2020

代理人:

摘要：

The present application provides a class of cell necrosis inhibitors as well as preparation methods and uses thereof. Specifically, the present application provides an inhibitor for inhibiting cell necrosis and/or human receptor interacting protein 1 kinase (RIP1). The agent has the structure shown in Formula I below. The compound and the composition containing it can be used for preventing and/or treating diseases involving cell death and/or inflammation.本申請案提供一類細胞壞死抑制劑及其製備方法和用途，具體而言，本申請案提供一種抑制細胞壞死及/或人受體相互作用蛋白1激酶(RIP1)之抑制劑，所述之抑制劑具有如下式I所示之結構。該化合物及包含其之組合物可用於預防及/或治療涉及細胞死亡及/或發炎之疾病。

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/