There is provided a condom having a coating or deposit of a composition which includes a physiologically active agent such as glyceryl trinitrate wherein the condom has been treated with a neutralising or acidic material such that the condom when immersed in water results in the water having a p H of 7 or less. The condom may be treated with an acidic slurry of dusting powder. Also provided is a process for the manufacture of condoms in which the process includes the steps of: 1) treating the formed condoms with a neutralising or acidic material and 2) thereafter applying to the condoms a composition including a physiologically active agent such as glyceryl trinitrate wherein the condoms when immersed in water results in the water having a p H of 7 or less.
