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New pyrrolo (3,2-d) pyrimidine-4-derivatives and their uses for treatment
专利权人:
ASTRAZENECA AB
发明人:
BOEGEVIG, ANDERS,LO-ALFREDSSON, YVONNE,PIVONKA, DONALD,TIDEN, ANNA-KARIN
申请号:
DK05812036
公开号:
DK1824855T3
申请日:
2005.12.05
申请国别(地区):
DK
年份:
2012
代理人:
摘要:
There are disclosed novel compounds of formula (I) wherein R1, R12, L, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme MPO and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders, cardiovascular disorders and respiratory disorders.
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