BALOG, James Aaron,SISTLA, Ramesh Kumar,CHERUKU, Srinivas,THANGATHIRUPATHY, Srinivasan,KANYABOINA, Yadagiri,PULICHARLA, Nagalakshmi,AUDRIS, Huang,CHERNEY, Emily Charlotte,MARKWALDER, Jay A.,SEITZ, Ste
申请号:
USUS2016/025544
公开号:
WO2016/161279A1
申请日:
2016.04.01
申请国别(地区):
US
年份:
2016
代理人:
摘要:
There are disclosed compounds of formula (I) that modulate or inhibit the enzymatic activity of indoleamine-2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.L'invention concerne des composés de formule (I) qui modulent ou inhibent l'activité enzymatique de l'indoléamine 2,3-dioxygénase (IDO), des compositions pharmaceutiques contenant lesdits composés, et des méthodes de traitement des affections proliférantes, telles que le cancer, les infections virales et/ou les affections inflammatoires à l'aide des composés de l'invention.