NOVEL ALKYLATING AGENT FOR ALKYLATING TARGET WITH DRIVER ONCOGENE MUTATION

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专利权人:

发明人:

Hiroki NAGASE,Hiroshi SUGIYAMA,Toshikazu BANDO

申请号：

US15027877

公开号：

US20160310605A1

申请日:

2014.10.14

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides a novel alkylating agent specifically binding to the genetic mutation site of a driver oncogene. There are provided are a complex formed by binding an alkylating agent to a pyrrole imidazole polyamide specifically binding to the genetic mutation site of a driver oncogene, a driver oncogene mutation-specific alkylating agent comprising the aforementioned complex, and a pharmaceutical composition comprising the aforementioned complex.

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中国工程科技知识中心

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http://www.ckcest.cn/home/