The present invention relates to a medical composition and method for preparation utilizing human hair, includes steps of preparing a hair material as sampling chosen by the healthy hair of human body, after treatment of cleaning and sterilization to receive a further hair material, which the lipid content is lower 3% and water content is lower 10%, and then it is crushed in way of physical mode into a hair crushing powder, wherein the average of the particle size of the hair crushing powder is lower 2000μm. After blending the hair crushing powder and biodegradable polymer for Bio-reaction, which can be further made into the medical composition.本發明揭露一種由人體毛髮製成的醫用組合物及其製備，包括以下處理程序：取樣程序、洗淨程序、乾燥滅菌程序、顆粒化程序以及混摻程序；其中取樣程序係為提取生檢自個體的毛髮中特定部分作為一毛髮樣品；該洗淨程序係為洗滌該毛髮樣品以脫除該毛髮樣品之外部脂質，以取得毛髮脂質含量低於3%的一去脂毛髮樣品；該乾燥滅菌程序係為脫除該去脂毛髮樣品中的水分及細菌，以取得含水量低於10%以下的一脫水毛髮樣品；該顆粒化程序係為研磨粉碎該脫水毛髮樣品，以取得平均粒徑約小於2000μm的一毛髮粉碎物；該混摻程序係為將該毛髮粉碎物與一生物降解聚合物進行混摻以完成該醫用組合物。藉此，以不破壞角蛋白初始結構的處理方式，將人體自身毛髮經洗淨滅菌及物理性粉碎方式後所得之微米結構粉體，直接與降解性高分子進行混摻，製備出用於治療自身病理或整形美容用之醫療材料。
