Rongxiu LI,Li ZHANG,Conghao ZHONG,Chao CHENG,Aizhang XU,Wuguang LU,Zhibing Lin
申请号：
US14891351
公开号：
US20160206732A1
申请日:
2014.05.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides recombinant protein carrying an epitope. The recombinant protein has a skeleton structure from carrier protein, and a low immunogenic protein epitope is imported through splicing, replacement, and/or insertion to at least one molecular surface amino acid residue area of the carrier protein. The carrier protein has at least one T cell epitope, and the recombinant protein can effectively excite immunoreaction of an organism to the low immunogenic protein epitope.
