Process and intermediate compounds useful in the preparation of statins, particularly rosuvastatin

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专利权人:

发明人:

David J. Moody,Jonathan W. Wiffen

申请号：

US14225018

公开号：

US09024025B2

申请日:

2014.03.25

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Provided are a compound of formula (5) and a process for its preparationwherein: R1 represents an alkyl group R2 represents an aryl group R3 represents a protecting group or an alkyl group R4 represents a protecting group or a SO2R5 group where R5 is an alkyl group R6 represents (PR7R8)+X− or P(═O)R7R8 in which X is an anion and R7 and R8 each independently is an alkyl, aryl, alkoxy, or aryloxy group P1 represents hydrogen or a protecting group and W represents ═O or OP2, in which P2 represents hydrogen or a protecting group.

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