Michael Oestergaard,Punit P. Seth,Shuling Guo,Noriko Satake,Nitin Nitin,Joseph M. Tuscano
申请号：
US14871862
公开号：
US20160090598A1
申请日:
2015.09.30
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present disclosure provides compounds comprising modified oligonucleotides and anti-CD22 antibodies. Certain such modified oligonucleotides conjugated to anti-CD22 antibodies are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount activity or expression of the target nucleic acid in a cell.
