BRANDON, STEPHEN F.,OKERHOLM, RICHARD A.,LEGG, THOMAS J.
申请号:
CA2964581
公开号:
CA2964581C
申请日:
2017.04.18
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
Disclosed are high loading, controlled-release dosage forms for oraladministration ofmagnesium salts. For example, an oral dosage form can comprise from about 80%to about 95%magnesium lactate and one or more components. As another example, an oraldosage form cancomprise at least about 50% magnesium salt and exhibit a controlled releasedissolution profile.Also disclosed are methods for making controlled release dosage forms for oraladministration ofa therapeutically effective amount of magnesium salt to a mammal. Alsodisclosed are methodsfor treating a disorder characterized by magnesium deficiency and methods forpreventing oralleviating low magnesium levels.