用於基因治療的腺伴隨病毒載體的鞘內給藥

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专利权人:

The Trustees of The University of Pennsylvania;賓夕法尼亞州大學信託人

发明人:

WILSON, James, M.,HINDERER, Christian,ROTHWELL, William, Thomas,C‧辛德勒,ROTHWELL, William, Thomas,W‧T‧羅斯維爾

申请号：

HK18114021

公开号：

HK1257801A1

申请日:

2018.11.02

申请国别(地区):

HK

年份:

2019

代理人:

摘要：

A composition comprising at least one AAV vector formulated for intrathecal delivery to the central nervous system is described. The composition comprises at least one expression cassette which contains sequences encoding an immunoglobulin construct linked to expression control sequences therefor and a pharmaceutically acceptable carrier. The immunoglobulin construct may be an immunoglobulin modified to have decreased or no measurable affinity for neonatal Fc receptor (FcRn).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/