LIQUID COMPOSITIONS OF FACTOR VII POLYPEPTIDES

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专利权人:

NOVO NORDISK HEALTH CARE AG

发明人:

HANSEN, BIRTHE,JENSEN, MICHAEL,KORNFELT, TROELS

申请号：

AT04738944

公开号：

AT547114T

申请日:

2004.06.24

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

The invention concerns a liquid aqueous composition comprising (i) a factor VII polypeptide, (ii) an agent suitable for keeping pH in the range of from about 4.0 to about 9.0； (iii) an agent selected from the group consisting of: a calcium salt, a magnesium salt, or a mixture thereof； wherein the concentration of (iii) is less than 15 mM； and (iv) An ionic strength modifying agent； wherein the ionic strength of the composition is at least 200 mM.

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