Agensys; Inc.;Agensys, Inc.;Seattle Genetics, Inc.
发明人:
Morrison, Robert Kendall,An, Zili,Morrison, Karen Jane Meyrick,Snyder, Josh,Jia, Xiao-chi
申请号:
AU2018220120
公开号:
AU2018220120A1
申请日:
2018.08.24
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018220120A120180913.pdf#####ABSTRACT Antibody drug conjugates (ADC's) that bind to 158P 1 D7 protein and variants thereof are described herein. 158P1D7 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.