The Compound N - (6 - ((2R, 3S) - 3,4 - dihidroxibutan - 2iloxi) - 2 - (4 - fluorobenciltio pyrimidin-2-yl) - 4 - yl) - 3 - 1 - metilacetidina sulfonamide, qumiocina receptor； Crystal form； Preparation Process； Intermediate Compound, Pharmaceutical Composition and use allergic rhinitis, Asthma, COPD, col syndrome On irritable, inflammatory bowel disease, including

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专利权人:

ASTRAZENECA AB

发明人:

CONNOLLY, STEPHEN,EBDEN, MARK RICHARD,LANGER, THOMAS,STEVEN, ALAN ROBERT,STEWART, CRAIG ROBERT,TOMLIN, PAULA MARGART,WILLIAMS, ANDREW JOHN,WALTERS, LAIN ALASTAIR STEWART

申请号：

CL2014000079

公开号：

CL2014000079A1

申请日:

2014.01.10

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

There is provided a compound which is (a) a pyrimidine sulfonamide of formula (I) or (b) a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. The compound is useful in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial.EL COMPUESTO N-(6-((2R,3S)-3,4-DIHIDROXIBUTAN-2iloxi)-2-(4-FLUOROBENCILTIO) PIRIMIDIN-4-ilo)-3-METILACETIDINA-1-SULFONAMIDA, RECEPTOR DE QUMIOCINA； FORMA CRISTALINA； PROCESO DE PREPARACIÓN； COMPUESTO INTERMEDIARIO； COMPOSICION FARMACEUTICA； Y SU USO EN ASMA, RINITIS ALERGICA, EPOC, SINDROME DE COLON IRRITABLE, ENFERMEDAD INTESTINAL INFLAMATORIA, ENTRE OTRAS

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