Sharon R. Engel;Milan Chytil;Qun Kevin Fang;Kerry L. Spear
发明人:
Milan Chytil,Sharon R. Engel,Qun Kevin Fang,Kerry L. Spear
申请号：
US13249166
公开号：
US08404670B2
申请日:
2011.09.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided herein are fused imidazolyl compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.
