DE VISSER PETER CHRISTIAN,MULDERS SUSAN ALLEGONDA MARIA
申请号：
NZ70056113
公开号：
NZ700561A
申请日:
2013.04.23
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
The current invention provides an improved oligonucleotide consisting of a 2&rsquo-O-methyl RNA nucleotide residue, having a backbone wherein all phosphate moieties are replaced by phosphorothioate moieties, having a base sequence consisting of (XYG)7 wherein each X is 5-methylcytosine and each Y is Uracil and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.
