Provided, among other things, is a method of treating an indication of mucosalor adjacent tissue comprising periodically applying to mucosa at or adjacentto disease affected tissue a delivery device comprising a backing layer and anadhesive reservoir comprising an effective amount of appropriate compositionof plant extract(s) comprising extract of Sambucus nigra, wherein the adhesivereservoir comprises 30 to 70 polymer by weight, of which a major portioncomprises polyacrylic polymer, wherein the delivery device is flexible andtissue conforming.